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Nioxin

Nioxin System 4 Scalp Leave-In Treatment

  • Item Volume: 6.8 fl oz
  • Item Form: Cream
  • Scent Name: Peppermint Oil
  • Hair Type: Thinning

Last refreshed Sep 7, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

A leave-in scalp treatment with niacinamide and biotin for colored, dry or damaged hair with visible thinning, meant to be added to the System 4 cleanser and conditioner rather than replace them.

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ASIN: B0054Y0PMKCategory: Scalp Treatments

Overview

Nioxin System 4's leave-in scalp treatment targets colored, dry and damaged hair with visible thinning, adding niacinamide and biotin to a scalp-focused formula meant to sit alongside System 4's cleanser and conditioner rather than replace them.

This is the third step of a three-part Nioxin system, a leave-in treatment rather than a shampoo, aimed specifically at hair that is already color-treated and showing progressed thinning. The brand's own testing claims are about density and fullness, not regrowth, and reviewer timelines back up that this is a slow, cumulative product rather than a quick fix.

  • Third step of the Nioxin System 4 routine
  • Niacinamide and biotin in a leave-in scalp formula
  • Brand testing cites majority gains in thickness, density, fullness
  • Built for colored, dry, damaged hair with progressed thinning

Who it's for

People with color-treated, dry or damaged hair who have noticed thinning and want a scalp-directed leave-in to pair with the rest of the Nioxin System 4 line. Less suited to anyone with sensitive eyes or skin, since the menthol and peppermint in the formula bothered at least one reviewer.

Pros and cons

Cons
  • Price draws repeated complaints as steep
  • Menthol and peppermint caused a dry-eye reaction for one reviewer
  • Results take months, not days, to show

Performance notes

The treatment leans on niacinamide and biotin plus botanical extracts to cleanse the scalp of sebum buildup and reduce breakage over time, and the brand cites internal testing showing a majority of consumers noticed thickening, density and fullness effects.

Specifications

BrandNioxin
Dimensions & fit
Item Weight0.43 pounds
Capacity & performance
Item Volume6.8 fl oz
Age Range DescriptionAdult
Included components
Unit Count6.8 fl oz
Other details
Item FormCream
Scent NamePeppermint Oil
Hair TypeThinning
Number Of Items1
Active IngredientsNicotinate
Item HighlightScalp Health / Hair Thickening Leave-In Treatment For Damaged Hair With Progressed Thinning / Maintain Vibrant Color
Recommended Uses For Productsalon

Frequently asked questions

Is this a standalone product or part of a system?

It is the leave-in treatment step of Nioxin System 4, meant to be used alongside the matching System 4 shampoo and conditioner.

Can the menthol in this formula cause irritation?

At least one reviewer reported a dry-eye reaction to the menthol and peppermint in the formula, so anyone with sensitive eyes should be cautious.