US
NATURE

Nature Made Vitamin B12 1000 mcg

  • Vitamin B12
  • Softgel
  • Vitamin B12
  • 150
4.7/ 5 on Amazon44,800Amazon ratings50,000+bought last month4.7ProductDome score
  • More reviewed than 98%
High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYou want a high-dose, single-ingredient B12 softgel with a long supply

A single-nutrient 1000 mcg B12 softgel sized for a five-month supply, aimed at buyers who want to dose B12 on its own.

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ProductDome scorecard

How it ranks among the 130 vitamin b12 we track

4.7/ 5ProductDome scoreHigh confidence
Owner satisfaction · 56% of scorecategory median 4.7★4.7

4.7★ across 44,800 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 2,250 ratings5.0

44,800 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score5.0

50,000+ bought on Amazon last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 130 vitamin b12 we track - how the scorecard works · full vitamin b12 data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

Nature Made's model 2916 softgel delivers 1000 mcg of vitamin B12 per dose, sized as a 150-count bottle meant to last 150 days at one softgel a day. It's positioned for energy metabolism support rather than as part of a B-complex blend.

B12 is one of the more commonly supplemented vitamins for people watching energy levels or following diets that limit animal products. Nature Made packages this as a single-nutrient softgel rather than folding it into a multivitamin, which suits buyers who want to control the B12 dose on its own. The allergen line lists soy, worth checking for anyone avoiding it.

  • 1000 mcg vitamin B12 per softgel
  • 150 softgels, a 150-day supply
  • Gluten free formula
  • Allergen line lists soy

Who it's for

Fits adults who want a straightforward, high-dose B12 softgel without extra ingredients mixed in. Less useful for anyone who wants B12 alongside other B vitamins in one product, or who needs to avoid soy.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • 1000 mcg B12 per softgel
  • 150-day supply in one bottle
  • Gluten free formula
What to check first
  • Allergen line lists soy
  • Single nutrient only, no B-complex blend

Performance notes

At one softgel a day, the 150-count bottle covers roughly five months before a refill is needed. The formula is built around B12 alone at 1000 mcg, positioned for energy metabolism support rather than broader multivitamin coverage.

Specifications

BrandNATURE
Model2916
FormSoftgel
Supplement TypeVitamin B12
Count150
FlavorUnflavored
BenefitsEnergy Metabolism Support
DietGluten Free
AllergensGluten Free, Soy

How it compares

This product against the closest alternatives we track in vitamin b12.

ProductAmazon ratingRatingsProductDome score
Nature Made Vitamin B12 1000 mcgThis product4.7 / 544,8004.7 / 5
Nature's Bounty Vitamin B12 2500 mcgNature’s4.8 / 526,8004.7 / 5
Solgar Vitamin B12 1000 mcgSolgar4.8 / 511,5004.7 / 5
Natrol Vitamin B12 5000 mcg Fast Dissolve B12 SupplementNatrol4.7 / 540,3004.6 / 5
vitafusion Extra Strength Vitamin B12 GummiesVitafusion4.7 / 532,2994.6 / 5
Frequently asked

Questions about the NATURE 2916

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

How much B12 is in each Nature Made 2916 softgel?

1000 mcg per softgel.

How long does a bottle of 150 softgels last?

About 150 days at one softgel per day.

Does this product contain soy?

The listed allergen line names soy, so check that before buying if you avoid it.