Isotonix OPC-3 Antioxidant Supplement
- Combination Supplement
- Powder
- Grape Seed Extracts
- 10.6 ounces
- Better rated than 59%
- More reviewed than 57%
Isotonix OPC-3 suits people comfortable mixing a daily powder drink for a multi-source antioxidant blend aimed at circulatory support.
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How it ranks among the 61 combination supplement we track
4.6★ across 1,245 Amazon ratings, Bayesian-smoothed toward the category average.
1,245 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
1,000+ bought on Amazon last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 61 combination supplement we track - how the scorecard works · full combination supplement data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
Isotonix OPC-3 is a powdered antioxidant supplement built around Pycnogenol, grape seed extracts, bilberry, red wine and pine bark extracts, mixed as an isotonic drink for heart and circulatory support. It comes in a grape-flavored 10.6 ounce container providing 90 servings.
The isotonix branding refers to how the powder is meant to be mixed, as an isotonic solution matching the body's own fluid concentration, which is a delivery approach rather than an added active ingredient. The antioxidant blend draws from several plant sources, grape seed, bilberry, pine bark, red wine extract, rather than a single compound. It is vegan and gluten free.
- Pycnogenol, grape seed, bilberry, red wine and pine bark extracts
- Isotonic powder for circulatory support
- Grape flavored, 10.6 ounce container
- 90 servings, vegan and gluten free
Who it's for
Suits people who prefer a mixed powder drink over capsules for a multi-source antioxidant blend aimed at circulatory support. Not the choice for anyone who wants capsules or a single-antioxidant product.
Strengths and trade-offs
Drawn from this product's published specifications.
- Multi-source antioxidant blend of Pycnogenol, grape seed, bilberry and pine bark
- Vegan and gluten free
- 90 servings per container, about three months of daily use
- Requires mixing a powder drink rather than taking a capsule
- Grape flavor may not suit everyone
Performance notes
The formula blends Pycnogenol, grape seed extract, bilberry, red wine extract and pine bark extract, positioned for heart and circulatory support, delivered as an isotonic powder meant to be mixed into liquid. The 10.6 ounce container yields 90 servings, so daily use spans about three months.
Specifications
| Brand | Isotonix |
|---|---|
| Model | AX-AY-ABHI-101410 |
| Form | Powder |
| Supplement Type | Grape Seed Extracts |
| Count | 10.6 ounces |
| Flavor | Grape |
| Diet | Gluten Free |
| Allergens | Dairy Free, Gluten Free |
How it compares
This product against the closest alternatives we track in combination supplement.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Isotonix OPC-3 Antioxidant SupplementThis product | 4.6 / 5 | 1,245 | 4.3 / 5 |
| Carlyle Tart Cherry Extract CapsulesCarlyle | 4.6 / 5 | 11,200 | 4.6 / 5 |
| Integrative Therapeutics Active B-ComplexIntegrative | 4.6 / 5 | 7,500 | 4.6 / 5 |
| Heliocare Skin Care Dietary Supplement: 240mg Polypodium Leucotomos Extract PillsHeliocare | 4.6 / 5 | 5,700 | 4.5 / 5 |
| Pure Encapsulations NAC 600 mgPURE | 4.7 / 5 | 3,800 | 4.6 / 5 |
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Questions about the Isotonix AX-AY-ABHI-101410
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
How is Isotonix OPC-3 taken?
It's a powder meant to be mixed into liquid as an isotonic drink, not swallowed as a capsule.
What flavor is the powder?
Grape.
How many servings are in a container?
90 servings per 10.6 ounce container.