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Smiling

Smiling Paws Pets Advanced Chlorhexidine & Ketoconazole Spray for Cats & Dogs Spray 8oz

  • Skin Supplement
  • 1
  • White
  • 9.9 ounces
4.4/ 5 on Amazon1,300Amazon ratings800+bought last month4.2ProductDome score
  • Better rated than 55%
  • More reviewed than 55%
High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYou specifically need a chlorhexidine and ketoconazole spray for topical use on a dog or cat.

A topical spray combining chlorhexidine and ketoconazole for cats and dogs, best treated as a skin-care product to apply as directed on the label.

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ProductDome scorecard

How it ranks among the 71 skin supplements we track

4.2/ 5ProductDome scoreHigh confidence
Owner satisfaction · 56% of scorecategory median 4.3★4.4

4.4★ across 1,300 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 956 ratings3.9

1,300 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score3.9

800+ bought on Amazon last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 71 skin supplements we track - how the scorecard works · full skin supplements data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

Smiling Paws Pets' 8 oz spray combines chlorhexidine and ketoconazole in a topical formula for cats and dogs. Sold under the Advanced name, it's applied directly to the coat and skin rather than mixed into food or water.

Amazon files this under Skin Supplements, but the ingredient combination and spray format point to a topical antiseptic rather than an ingested supplement, so treat the category label as imprecise. Limited attribute data is available beyond the ingredient names and packaging, so specific use directions should come from the product label rather than this listing.

  • 8 oz spray bottle
  • Chlorhexidine and ketoconazole formula
  • For use on cats and dogs

Who it's for

Owners looking for a topical chlorhexidine and ketoconazole spray to apply to a dog or cat's skin. Anyone needing dosing or condition-specific guidance should check the label rather than relying on this listing alone.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • Combines two named topical actives in one spray
  • 8 oz size, ready to spray without mixing
What to check first
  • Listing provides minimal detail on concentration or specific use directions
  • No customer review text is available in this data to gauge results

Performance notes

Chlorhexidine and ketoconazole are the two named active ingredients, packaged as a ready-to-use 8 oz spray. Beyond the ingredient names and bottle size, the listing provides little detail on concentration or intended condition, so following the product's own label directions is the safest approach.

Specifications

BrandSmiling
ModelSPP2
Dimensions & fit
Item Weight9.9 ounces
Item Package Dimensions L X W X H7.9 × 1.8 × 1.6 inches
Item Dimensions Lxwxh2 × 2 × 8 inches
Size8 ounces
Construction & materials
ColorWhite
Other details
Number Of Items1
Item Model NumberSPP2
ManufacturerSmiling Paws Pets T.J
Customer Reviews{'ratings_count': '1,311', 'stars': '4.4'}
Date First AvailableOctober 18, 2021
Target Audience Keyworddogs
AsinB083HX7X8S

How it compares

This product against the closest alternatives we track in skin supplements.

ProductAmazon ratingRatingsProductDome score
Smiling Paws Pets Advanced Chlorhexidine & Ketoconazole Spray for Cats & Dogs Spray 8ozThis product4.4 / 51,3004.2 / 5
Veterinary Formula Clinical Care Antiseptic and Antifungal Medicated Spray for Dogs & CatsVeterinary4.5 / 527,8054.5 / 5
Pet MD Hydrocortisone Spray for DogsPET4.3 / 516,2184.4 / 5
Zymox Veterinarian Strength Topical Cream with 1% Hydrocortisone for Dogs and CatsZYMOX4.5 / 54,4434.4 / 5
Vetericyn Plus Hot Spot Spray for Dogs Skin Sores and IrritationsVetericyn4.4 / 53,8464.4 / 5
Frequently asked

Questions about the Smiling SPP2

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

Is this spray for cats, dogs, or both?

It's labeled for both cats and dogs.

What are the active ingredients?

Chlorhexidine and ketoconazole.

How is it applied?

It's a spray, applied topically to the coat and skin.