Cetaphil 0299.011601 Moisturizer
- Moisturizer
- Tube
- Hypoallergenic
- 48 fl oz
- More reviewed than 86%
A large, hypoallergenic Cetaphil cream combining niacinamide and retinol, sized for high-volume use rather than a trial.
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How it ranks among the 323 moisturizers we track
4.4★ across 2,700 Amazon ratings, Bayesian-smoothed toward the category average.
2,700 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
Modest tracked demand last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 323 moisturizers we track - how the scorecard works · full moisturizers data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
Cetaphil's 0299.011601 moisturizer is a fragrance-free, oil-free cream formulated with niacinamide and retinol, packaged at a large 48.01 fluid ounce size in a tube and marked hypoallergenic.
At just over 48 ounces, this is a pump or bulk-scale size rather than the smaller tubes Cetaphil typically sells at retail, worth confirming before buying if you expected a standard bottle. Combining niacinamide with retinol in one cream is a fairly active formulation for a moisturizer, pairing a brightening ingredient with an anti-aging one rather than being a purely basic barrier cream. Hypoallergenic and oil-free labeling points it at sensitive or acne-prone skin that still wants those actives.
- Size: 48.01 fluid ounces
- Key ingredients: niacinamide, retinol, vitamin B3
- Oil-free and hypoallergenic
- Unscented, tube container
Who it's for
People who want niacinamide and retinol in a single daily moisturizer and go through cream fast enough to justify the large size. Not practical for someone who wants to sample a small tube first or has skin unaccustomed to retinol.
Strengths and trade-offs
Drawn from this product's published specifications.
- Combines niacinamide and retinol in one cream
- Oil-free, hypoallergenic formula
- Large 48 oz size reduces reorder frequency
- Retinol can irritate skin unaccustomed to it
- Large size is a big commitment if untested first
Performance notes
Retinol is an active ingredient that increases cell turnover and can cause irritation or purging when skin isn't used to it, so pairing it with niacinamide, which has some soothing and brightening properties, is a common way to balance a formula's tolerability. Oil-free and hypoallergenic labeling suggests the base cream is built to minimize additional irritation, but retinol tolerance still varies person to person enough that a new user should expect an adjustment period regardless of the base formula.
Specifications
| Brand | Cetaphil |
|---|---|
| Model | 0299.011601 |
| Dimensions & fit | |
| Size | 48 fl oz |
| Capacity & performance | |
| Age Range | Adult |
| Construction & materials | |
| Material | Hypoallergenic |
| Other details | |
| Container | Tube |
| Free Of | Oil Free |
| Item Form | Cream |
| Key Ingredients | niacinamide,retinol,vitamin b3 |
| Scent | Unscented |
Other Cetaphil moisturizers
How it compares
This product against the closest alternatives we track in moisturizers.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Cetaphil 0299.011601 MoisturizerThis product | 4.4 / 5 | 2,700 | 3.9 / 5 |
| Bubble Skincare 104000 MoisturizerBubble Skincare | 4.8 / 5 | 6,900 | 4.7 / 5 |
| Skin1004 8809576261134 MoisturizerSkin1004 | 4.6 / 5 | 9,500 | 4.5 / 5 |
| Beauty of Joseon 8809954941498 MoisturizerBeauty of Joseon | 4.5 / 5 | 7,400 | 4.5 / 5 |
| Dr.Althea 8809447256221 MoisturizerDr.Althea | 4.6 / 5 | 18,200 | 4.4 / 5 |
Similar moisturizers from other brands
Questions about the Cetaphil 0299.011601
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
What active ingredients are in the Cetaphil 0299.011601 moisturizer?
Niacinamide, retinol, and vitamin B3.
How large is this Cetaphil moisturizer?
48.01 fluid ounces, a bulk size rather than a standard retail tube.
Is the Cetaphil 0299.011601 moisturizer oil-free?
Yes, it's labeled oil-free and hypoallergenic.