Natural

Natural Factors RxOmega-3 Ultra Strength

Omega-3
Softgel
Omega-3 Fatty Acids
150

4.7/ 5 on Amazon676Amazon ratings800+bought last month4.3ProductDome score

High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology

Best forYou want a concentrated fish oil EPA/DHA softgel and don't mind two per serving

A two-softgel-serving fish oil omega-3 with EPA and DHA, gluten free in formulation but not suitable for anyone with a fish allergy.

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ProductDome scorecard

How it ranks among the 131 omega-3 we track

4.3/ 5ProductDome scoreHigh confidence

Owner satisfaction · 56% of scorecategory median 4.6★4.7

4.7★ across 676 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 1,400 ratings3.5

676 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score3.9

800+ bought on Amazon last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 131 omega-3 we track - how the scorecard works · full omega-3 data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

Natural Factors packages this fish-oil omega-3 as 150 softgels providing EPA and DHA, marketed toward brain, heart and eye health support. The 75-serving count implies two softgels per serving.

Ultra Strength omega-3 softgels compete mainly on how much EPA and DHA they pack per dose, and this one is built around a two-softgel serving rather than a single capsule. It is gluten free but derived from fish, so it carries a fish allergen and is not suitable for anyone avoiding animal-derived omega-3.

EPA and DHA omega-3 fatty acids
150 softgels, 75 servings
Gluten free
Fish-derived, contains fish allergen

Who it's for

People comfortable taking two softgels per serving in exchange for a concentrated fish-oil dose are the right buyer. Anyone with a fish allergy or a preference for plant-based omega-3 should pick a different product.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out

Combines EPA and DHA in one softgel
Gluten free formula
150-count bottle gives a 75-day supply

What to check first

Fish-derived, unsuitable for fish allergies
Two softgels required per serving

Performance notes

The 150-count bottle is portioned at 75 servings, meaning each two-softgel serving delivers the labeled EPA and DHA dose together rather than split across a single capsule.

Specifications

Brand	Natural
Model	35493
Form	Softgel
Supplement Type	Omega-3 Fatty Acids
Count	150
Flavor	Fish
Benefits	Immune Support
Diet	Gluten Free
Allergens	Fish

How it compares

This product against the closest alternatives we track in omega-3.

Product	Amazon rating	Ratings	ProductDome score
Natural Factors RxOmega-3 Ultra StrengthThis product	4.7 / 5	676	4.3 / 5
Nature Made Fish Oil Omega 3 SupplementsNATURE	4.8 / 5	11,000	4.7 / 5
NOW Supplements, Omega-3 180 EPA / 120 DHA, Molecularly Distilled, Cardiovascular…Now	4.8 / 5	7,400	4.7 / 5
Nordic Naturals Ultimate OmegaNordic	4.7 / 5	59,000	4.6 / 5
NatureWise Extra-Strength Omega 3 Fish Oil SupplementNatureWise	4.7 / 5	9,500	4.6 / 5

Frequently asked

Questions about the Natural 35493

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

How many softgels are in one serving?

One serving is two softgels.

How long does one bottle last?

At one serving a day, 150 softgels last about 75 days.

Is this omega-3 fish based?

Yes, it is a fish oil softgel and lists fish as an allergen.