US
ZYMOX

Zymox Advanced Otic Plus Ear Solution with Hydrocortisone 1.25 oz

  • Size: 0.12 Pounds
  • Item Weight: 0.08 pounds
  • Target Audience Keyword: dogs, house-cats
  • Color: Original Version

Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

A straightforward one-a-day ear treatment combining an enzymatic base with hydrocortisone for a standard seven day course.

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ASIN: B0066VLPGACategory: Pet Ear Care Products

Overview

An enzymatic ear solution for dogs and cats with 1 percent hydrocortisone added, sold in a 1.25 ounce bottle intended for daily external ear application.

The enzymatic formula is designed to work on the ear's natural chemistry, with the hydrocortisone added for itch and inflammation relief, and the directions call for a single daily application worked into the ear canal for seven days rather than an ongoing rinse. It's for external use only.

  • 1.25 oz bottle
  • 1% hydrocortisone added
  • Once-daily use for 7 days
  • For dogs and cats, external use only

Who it's for

Suited to dog and cat owners dealing with ear irritation who want a single formula that combines an enzymatic base with hydrocortisone. Owners needing a diagnosis for a specific ear infection should still check with a vet.

Pros and cons

Pros
  • Combines enzymatic action with 1% hydrocortisone
  • Simple once-daily, seven day directions
  • Works on both dogs and cats
Cons
  • Small 1.25 oz bottle for a seven day course
  • External use only, not a substitute for a vet diagnosis

Performance notes

Directions call for applying to an uncleaned ear, filling the canal, massaging it in, wiping away excess and letting the pet shake its head, once a day for seven days. Afterward, the brand suggests following up with its plain Otic flush if needed. The bottle holds 1.25 ounces and is for external use only.

Specifications

BrandZYMOX
Dimensions & fit
Size0.12 Pounds
Item Weight0.08 poundslower than 90% of 40 pet ear care products
Item Package Dimensions L X W X H3.9 × 1.9 × 1.2 inches
Item Dimensions Lxwxh7.8 × 4.2 × 3.8 inches
Capacity & performance
Age Range DescriptionAll Life Stages
Construction & materials
ColorOriginal Version
Included components
Included Components37ML SOLUTION EAR
Other details
Target Audience Keyworddogs, house-cats
Number Of Items1
AsinB0066VLPGA
ManufacturerPet King Brands
Customer Reviews{'ratings_count': '14,770', 'stars': '4.7'}
Item Model Number441125
Date First AvailableNovember 12, 2011
DirectionsFor external use only. Shake bottle well before use. Apply to uncleaned ear, filling ear canal. Gently massage and work into area. Wipe to remove excess. Allow pet to shake head. Apply once daily for 7 days. If needed after course, use ZYMOX Otic to flush the ears.
Specific Uses For ProductEars
Model NameEar Solution 1%

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Frequently asked questions

How often is this applied?

Once daily for seven days, per the product directions.

Does it contain hydrocortisone?

Yes, 1 percent hydrocortisone is included in this Advanced Formula version.

Is it safe for both cats and dogs?

Yes, it's labeled for both dogs and house cats.