Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1%…
- Ear Care
- 1
- Original Version
- 1.3 ounces
- Better rated than 73%
- More reviewed than 92%
A straightforward one-a-day ear treatment combining an enzymatic base with hydrocortisone for a standard seven day course.
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How it ranks among the 63 ear care we track
4.7★ across 14,770 Amazon ratings, Bayesian-smoothed toward the category average.
14,770 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
20,000+ bought on Amazon last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 63 ear care we track - how the scorecard works · full ear care data report. Confidence: medium - useful but incomplete evidence.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
An enzymatic ear solution for dogs and cats with 1 percent hydrocortisone added, sold in a 1.25 ounce bottle intended for daily external ear application.
The enzymatic formula is designed to work on the ear's natural chemistry, with the hydrocortisone added for itch and inflammation relief, and the directions call for a single daily application worked into the ear canal for seven days rather than an ongoing rinse. It's for external use only.
- 1.25 oz bottle
- 1% hydrocortisone added
- Once-daily use for 7 days
- For dogs and cats, external use only
Who it's for
Suited to dog and cat owners dealing with ear irritation who want a single formula that combines an enzymatic base with hydrocortisone. Owners needing a diagnosis for a specific ear infection should still check with a vet.
Strengths and trade-offs
Drawn from this product's published specifications.
- Combines enzymatic action with 1% hydrocortisone
- Simple once-daily, seven day directions
- Works on both dogs and cats
- Small 1.25 oz bottle for a seven day course
- External use only, not a substitute for a vet diagnosis
Performance notes
Directions call for applying to an uncleaned ear, filling the canal, massaging it in, wiping away excess and letting the pet shake its head, once a day for seven days. Afterward, the brand suggests following up with its plain Otic flush if needed. The bottle holds 1.25 ounces and is for external use only.
Specifications
| Brand | ZYMOX |
|---|---|
| Model | 441125 |
| Dimensions & fit | |
| Item Weight | 1.3 ounces |
| Item Dimensions Lxwxh | 7.8 × 4.2 × 3.8 inches |
| Size | 2 ounces |
| Item Package Dimensions L X W X H | 3.9 × 1.9 × 1.2 inches |
| Capacity & performance | |
| Age Range Description | All Life Stages |
| Construction & materials | |
| Color | Original Version |
| Included components | |
| Included Components | 37ML SOLUTION EAR |
| Other details | |
| Number Of Items | 1 |
| Directions | For external use only. Shake bottle well before use. Apply to uncleaned ear, filling ear canal. Gently massage and work into area. Wipe to remove excess. Allow pet to shake head. Apply once daily for 7 days. If needed after course, use ZYMOX Otic to flush the ears. |
| Model Name | Ear Solution 1% |
| Specific Uses For Product | Ears |
| Asin | B0066VLPGA |
| Manufacturer | Pet King Brands |
| Customer Reviews | {'ratings_count': '14,770', 'stars': '4.7'} |
| Date First Available | November 12, 2011 |
| Target Audience Keyword | dogs, house-cats |
| Item Model Number | 441125 |
Other ZYMOX ear care
How it compares
This product against the closest alternatives we track in ear care.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1%…This product | 4.7 / 5 | 14,770 | 4.6 / 5 |
| Pet MD Dog Ear Cleaning WipesPET | 4.6 / 5 | 63,112 | 4.6 / 5 |
| Nutri-Vet Ear Cleanse for DogsNutri-Vet | 4.6 / 5 | 9,700 | 4.5 / 5 |
| Vetnique Oticbliss Dog Ear Infection Treatment Flush & Ear Cleaner for Dogs & CatsVetnique | 4.6 / 5 | 3,383 | 4.5 / 5 |
| TrizULTRA+Keto FlushTrizULTRA+Keto | 4.7 / 5 | 1,689 | 4.5 / 5 |
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Questions about the ZYMOX 441125
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
How often is this applied?
Once daily for seven days, per the product directions.
Does it contain hydrocortisone?
Yes, 1 percent hydrocortisone is included in this Advanced Formula version.
Is it safe for both cats and dogs?
Yes, it's labeled for both dogs and house cats.