ZYMOX Enzymatic Ear Solution with 0.5-Percent Hydrocortisone
- Ear Care
- 1.2 ounces
- 4 × 2 × 1.3 inches
- 3.9 × 1.9 × 1.3 inches
- Better rated than 73%
- More reviewed than 95%
A combination enzymatic and hydrocortisone ear solution in a small 1.25 oz bottle, suited to routine ear care for itchy or irritated ears in dogs and cats.
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How it ranks among the 63 ear care we track
4.7★ across 16,076 Amazon ratings, Bayesian-smoothed toward the category average.
16,076 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
5,000+ bought on Amazon last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 63 ear care we track - how the scorecard works · full ear care data report. Confidence: medium - useful but incomplete evidence.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
Enzyme-based ear solution for dogs and cats with 0.5 percent hydrocortisone added, sold in a 1.25 oz bottle sized for at-home ear maintenance rather than a full veterinary course.
The enzymatic approach differs from typical ear cleaners that rely on solvents or drying agents; it depends on an enzyme system to work in the ear canal, and the added hydrocortisone addresses itching and inflammation at the same time.
- 1.25 oz bottle
- 0.5% hydrocortisone included
- Enzymatic ear solution
- For dogs and cats
Who it's for
Owners managing ongoing ear irritation or discomfort in a dog or cat who want an enzyme and hydrocortisone combination rather than a plain cleaning rinse. Not a substitute for veterinary diagnosis if an ear infection is suspected.
Strengths and trade-offs
Drawn from this product's published specifications.
- Combines enzymatic action with hydrocortisone in one solution
- Small 1.25 oz size for at-home use
- Formulated for both dogs and cats
- Small bottle size means more frequent reordering for ongoing use
Performance notes
The enzyme system is designed to stay active in the moist environment of the ear canal, working alongside the hydrocortisone's anti-inflammatory effect rather than relying on alcohol or harsh solvents that can sting already irritated ears.
Specifications
| Brand | ZYMOX |
|---|---|
| Model | RZES0125W |
| Dimensions & fit | |
| Item Weight | 1.2 ounces |
| Item Dimensions Lxwxh | 4 × 2 × 1.3 inches |
| Item Package Dimensions L X W X H | 3.9 × 1.9 × 1.3 inches |
| Other details | |
| Asin | B007NVJAJG |
| Department | Pet Owners |
| Manufacturer | Pet King Brands, Inc. |
| Customer Reviews | {'ratings_count': '16,076', 'stars': '4.7'} |
| Date First Available | March 23, 2012 |
| Target Audience Keyword | Dog, dogs, house-cats |
| Item Model Number | RZES0125W |
Other ZYMOX ear care
How it compares
This product against the closest alternatives we track in ear care.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| ZYMOX Enzymatic Ear Solution with 0.5-Percent HydrocortisoneThis product | 4.7 / 5 | 16,076 | 4.6 / 5 |
| Pet MD Dog Ear Cleaning WipesPET | 4.6 / 5 | 63,112 | 4.6 / 5 |
| Nutri-Vet Ear Cleanse for DogsNutri-Vet | 4.6 / 5 | 9,700 | 4.5 / 5 |
| Vetnique Oticbliss Dog Ear Infection Treatment Flush & Ear Cleaner for Dogs & CatsVetnique | 4.6 / 5 | 3,383 | 4.5 / 5 |
| TrizULTRA+Keto FlushTrizULTRA+Keto | 4.7 / 5 | 1,689 | 4.5 / 5 |
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Questions about the ZYMOX RZES0125W
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
Is this solution safe for cats as well as dogs?
Yes, the label lists both dogs and house-cats as the target audience.
How much hydrocortisone does it contain?
0.5 percent.
What size bottle does it come in?
1.25 fl oz.