Pet Honesty Chlorhexidine Cat & Dog Seasonal Itch Relief Shampoo
- Dog Shampoo
- 16 fl oz
- Cat, Dog
- 16
- More reviewed than 89%
A medicated chlorhexidine and ketoconazole shampoo for cats and dogs aimed at itching and hot spots, more targeted than a general grooming shampoo.
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How it ranks among the 131 dog shampoos we track
4.6★ across 13,100 Amazon ratings, Bayesian-smoothed toward the category average.
13,100 Amazon ratings, weighted on a log scale so huge counts don't drown everything.
10,000+ bought on Amazon last month.
Brand identity, imagery, description and spec coverage.
The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 131 dog shampoos we track - how the scorecard works · full dog shampoos data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.
Overview
Pet Honesty's Chlorhexidine shampoo is a 16oz medicated wash for cats and dogs, formulated with 2% chlorhexidine gluconate and 1% ketoconazole for seasonal itching, hot spots, and skin irritation rather than routine coat cleaning.
Chlorhexidine gluconate and ketoconazole are antimicrobial and antifungal actives commonly used in medicated pet shampoos for skin issues tied to bacteria or yeast, which sets this apart from a plain cleansing or deodorizing shampoo. The listing sits under a Dog Shampoos category, but the target species field lists both cats and dogs. The ingredient list also includes aloe vera gel and a cucumber melon fragrance, plus FD&C Red 40 dye.
- 16oz medicated shampoo
- 2% chlorhexidine gluconate, 1% ketoconazole
- For cats and dogs
- Aloe vera gel included
Who it's for
Cat and dog owners dealing with hot spots, seasonal itching, or skin irritation who want a medicated wash rather than a standard cleaning shampoo. Not the pick for owners who want a fragrance-free or dye-free formula, since it contains added fragrance and FD&C Red 40.
Strengths and trade-offs
Drawn from this product's published specifications.
- Contains 2% chlorhexidine gluconate and 1% ketoconazole
- Labeled for both cats and dogs
- Includes aloe vera gel
- Contains added fragrance and FD&C Red 40 dye
- Listed under Dog Shampoos despite covering cats too
Performance notes
Chlorhexidine gluconate at 2% and ketoconazole at 1% are the working actives, targeting bacterial and yeast-related skin issues respectively, which is the typical basis for relief from hot spots and certain itch causes. Aloe vera gel is included to help soothe skin during the wash, and the formula is scented with cucumber melon fragrance rather than being unscented.
Specifications
| Brand | PET |
|---|---|
| Model | AS-TP-4106 |
| Capacity & performance | |
| Liquid Volume | 16 fl oz |
| Construction & materials | |
| Material Type Free | Non-GMO |
| Included components | |
| Unit Count | 16 |
| Included Components | Yes |
| Warranty & support | |
| Warranty Description | Lifetime |
| Other details | |
| Pet Type | Cat, Dog |
| Manufacturer Part Number | 850005524106 |
| Allergen Information | Non-GMO |
| Model Number | AS-TP-4106 |
| Scent Name | Chlorhexidine - Shampoo |
| Target Species | Cat,Dog |
| Upc | 850005524106 |
| Product Benefits | Cleansing |
| Asin | B07K6JSBRB |
| Customer Reviews | {'ratings_count': '13,116', 'stars': '4.6'} |
| Manufacturer | Pet Honesty |
| Special Ingredients | Chlorhexidine Gluconate 2%, Ketoconazole 1%. Purified Water, Sodium C14-16 Olefin Sulfonate, Cocamidopropyl Betaine, Octoxynol-10, Cucumber Melon Fragrance, Methyl Glucose Dioleate, Methylchloroisothiazolinone, Methylisothiazolinone, Hydrochloric Acid, Aloe Vera Gel, FD&C Red 40. |
| Best Sellers Rank | #456 in Pet Supplies (See Top 100 in Pet Supplies) #4 in Dog Shampoos |
| Recommended Uses For Product | Rashes |
| Item Form | Liquid |
Other PET dog shampoos
How it compares
This product against the closest alternatives we track in dog shampoos.
| Product | Amazon rating | Ratings | ProductDome score |
|---|---|---|---|
| Pet Honesty Chlorhexidine Cat & Dog Seasonal Itch Relief ShampooThis product | 4.6 / 5 | 13,100 | 4.6 / 5 |
| earthbath, Oatmeal & Aloe Dog Shampoo - Oatmeal Shampoo for Dogs, Itchy, Dry Skin Relief…earthbath | 4.7 / 5 | 8,500 | 4.6 / 5 |
| Douxo S3 PYO Medicated Dog Shampoo with 3% Chlorhexidine for DogsDouxo | 4.7 / 5 | 7,800 | 4.6 / 5 |
| Wahl USA Dry Skin & Itch Relief Pet Shampoo for DogsWAHL | 4.6 / 5 | 42,700 | 4.6 / 5 |
| Arm & Hammer Deodorizing Dog Shampoo with Baking Soda for Odor ControlARM | 4.6 / 5 | 22,400 | 4.6 / 5 |
Similar dog shampoos from other brands
Questions about the PET AS-TP-4106
Common buyer questions answered straight from the product spec data - no fluff, no "it depends".
Can this shampoo be used on cats?
Yes, the target species field lists both cats and dogs even though the listing category says Dog Shampoos.
What are the active ingredients?
Chlorhexidine gluconate at 2% and ketoconazole at 1%, both antimicrobial actives.
Is it fragrance-free?
No, it includes a cucumber melon fragrance and FD&C Red 40 dye.