Vetoquinol Zylkene Calming Capsules Small Cats & Dogs 30 Count
- Product Benefits: Anxiety Relief,Promote Relaxation,Reduce Stress
- Item Form: Capsule
- Dog Breed Size: Small
- Target Species: Dog
Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.
A milk-protein calming capsule sized for small dogs and cats, useful for short-term situational stress rather than ongoing behavioral treatment.
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ASIN: B07S5KTWLQCategory: Pet Calming Aids
Overview
Zylkene is an oral capsule built around alpha-casozepine, a compound derived from hydrolyzed bovine milk protein, dosed at 75 mg per capsule for dogs and cats in the 11 to 22 lb range. It is marketed for situational stress rather than daily sedation.
The active ingredient here is a milk-derived peptide, not a drug in the sedative sense, which is why Vetoquinol positions it as non-drowsy. That distinction matters for owners who want a dog alert during a vet visit or move, not knocked out. It is lactose-free despite the milk origin, since the processing isolates the protein fraction.
- 75 mg alpha-casozepine per capsule
- Derived from hydrolyzed bovine milk protein
- 30 capsules per package
- Formulated for dogs and cats 11-22 lb
Who it's for
Owners managing predictable stress events, boarding, travel, fireworks, or vet trips, for a small dog or cat between 11 and 22 lb. It is not framed as a treatment for chronic or severe anxiety disorders.
Pros and cons
- Non-drowsy formula for situational stress
- Lactose-free despite milk protein source
- Sized specifically for small dogs and cats
- Only fits the 11-22 lb weight range
- Not intended for severe or chronic anxiety
Performance notes
Alpha-casozepine works by binding to GABA receptors similarly to how the compound behaves in nursing infants after milk consumption, producing a calming effect without the grogginess associated with sedatives. Effects are generally described as gradual rather than immediate, so timing a dose well ahead of the stressful event matters more than with a fast-acting drug.
Specifications
| Brand | Vetoquinol |
|---|---|
| Dimensions & fit | |
| Dog Breed Size | Small |
| Included components | |
| Unit Count | 30 |
| Other details | |
| Product Benefits | Anxiety Relief,Promote Relaxation,Reduce Stress |
| Item Form | Capsule |
| Target Species | Dog |
| Flavor | Milk |
| Number Of Items | 1 |
| Specific Uses For Product | Anxiety, Moving, Stress, Thunderstorms |
| Asin | B07S5KTWLQ |
| Manufacturer | Vetoquinol |
| Best Sellers Rank | #2,654 In Pet Supplies (See Top 100 In Pet Supplies) #33 In Dog Relaxants |
| Customer Reviews | {'ratings_count': '3,660', 'stars': '4.1'} |
| Model Number | 424083 |
| Manufacturer Part Number | 424083 |
| Active Ingredients | Active Ingredients: Hydrolyzed Milk Protein (Bovine): 75 Mg (providing Alpha-Casozepine) |
Frequently asked questions
Will Zylkene make my dog drowsy?
No, it is formulated as non-drowsy, working through a milk-derived compound rather than a sedative.
Can cats take Vetoquinol Zylkene?
Yes, this size is labeled for small cats and dogs between 11 and 22 lb.
Is this safe for dogs with lactose sensitivity?
The capsule is lactose-free even though the active ingredient comes from milk protein.