Proferrin ES Heme Iron Polypeptide Tablets

Overview

Proferrin ES is a heme iron polypeptide supplement providing 10.5 mg of iron per tablet, made in the USA in a 90 tablet bottle, positioned as easier on the digestive system than standard iron supplements.

The distinguishing claim on this one is that heme iron polypeptide isn't blocked by coffee, calcium or proton pump inhibitors the way non-heme iron typically is, and that it's gentler on the gut, a common complaint with standard ferrous sulfate. At 10.5 mg per tablet the dose is lower than many standalone iron supplements, so people needing a higher dose may need to take more than one tablet.

• 10.5 mg heme iron polypeptide per tablet
• 90 tablets per bottle
• Made in the USA
• Gluten free

Who it's for

Suited to people who've had trouble tolerating standard iron supplements, including those on PPIs or who drink coffee with meals, since the label specifically calls out that this form isn't affected by those factors. Not the pick for someone who needs a very high single-tablet iron dose.

Pros and cons

Performance notes

Heme iron polypeptide is absorbed through a different pathway than the non-heme iron in most supplements, which is why the label states it isn't blocked by coffee, calcium or PPIs the way standard iron often is. That absorption route is also the reason it's marketed as gentler on the gut than typical ferrous sulfate tablets.

Specifications