US
Differin

Differin Adapalene Gel 0.1% Acne Treatment 45 g

  • 0.1% adapalene retinoid gel
  • 45 grams, 1.6 ounces, up to a 90 day supply
  • Acne preventing benefit, face only
  • Unscented and fragrance free
  • All skin types

Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

A face-only adapalene gel for acne, sold as a long-lasting tube and unscented. It is a retinoid medication, so it is not a moisturizer or cleanser, and the listing gives no directions.

As an Amazon Associate I earn from qualifying purchases. ProductDome earns a commission when you buy through links on this page.

ASIN: B01M114813Category: Skin Care Gels

Overview

A tube of retinoid acne gel for the face, Differin Adapalene uses adapalene as its listed ingredient. The title describes it as a prescription strength retinoid gel in a long-supply tube.

A retinoid designed to help prevent acne breakouts is a different step from a wash or a spot treatment, and a long supply suits a daily routine. The listing has no directions, warnings or ingredient list, so the box label matters.

Who it's for

Adults with acne who want a retinoid gel and are willing to follow label directions closely. Those with very sensitive skin, or who expect an overnight spot treatment, should speak to a clinician first.

Pros and cons

Pros
  • Adapalene retinoid gel
  • Long supply per tube
  • Unscented, fragrance free
  • Suits all skin types
Cons
  • Directions not on listing
  • Warnings not on listing
  • Not a cleanser or moisturizer

Performance notes

Adapalene works on how skin cells turn over inside pores, which helps prevent breakouts over weeks rather than hours. Early use can bring dryness or irritation, and the listing does not describe either effect.

Specifications

BrandDifferin
Dimensions & fit
Package Size Name90 Day Supply
Item weight0.1 Pounds
Size1.58 Ounce (Pack of 1)
Construction & materials
Material FeaturesFragrance Free
Included components
Unit Count1.6 Ounce
Other details
Skin TypeAll
Special IngredientsAdapalene 0.1%
Product BenefitsAcne Preventing
Target Use Body PartFace
Item FormGel
Scent NameUnscented

Closest rivals on specs

Compare all side by side

Frequently asked questions

Is Differin Adapalene Gel a moisturizer or a cleanser?

No. It is listed as a retinoid gel acne treatment for the face, with acne preventing as its benefit.

How long does one Differin tube last?

The title says up to a 90 day supply in a 45 gram tube.

Does Differin gel contain fragrance?

No. The scent is unscented and the features say fragrance free.