US
Differin

Differin Adapalene Gel 0.1% Acne Treatment

  • Gel
  • Acne Prone
  • 1 ounce
  • 2
4.5/ 5 on Amazon454Amazon ratings3.7ProductDome score
High confidenceLast refreshed Aug 4, 2026Amazon data + ProductDome analysis · methodology
Best forYou already tolerate adapalene and want a stocked two-tube supply.

A dermatologist-grade adapalene gel at drugstore pricing, useful if you already know retinoids work for your skin and want two tubes on hand.

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ProductDome scorecard

How it ranks among the 238 gels we track

3.7/ 5ProductDome scoreHigh confidence
Owner satisfaction · 56% of scorecategory median 4.6★4.5

4.5★ across 454 Amazon ratings, Bayesian-smoothed toward the category average.

Evidence strength · 17% of scorecategory median 461 ratings3.3

454 Amazon ratings, weighted on a log scale so huge counts don't drown everything.

Buyer demand · 11% of score0.0

Modest tracked demand last month.

Data quality · 11% of score3.8

Brand identity, imagery, description and spec coverage.

The ProductDome score is separate from the Amazon rating shown above: it combines the Bayesian-smoothed Amazon rating with evidence volume, tracked demand, and data quality across the 238 gels we track - how the scorecard works · full gels data report. Confidence: high - strong rating volume and complete data.Last refreshed Aug 4, 2026. Data-computed, not a hands-on test. Compiled by the ProductDome Research Team.

Overview

An OTC adapalene 0.1% gel for acne, sold as two 0.5 oz tubes from Galderma. Unscented and formulated for acne-prone skin, it's meant as a nightly retinoid step rather than a spot treatment.

Adapalene is a first-generation retinoid that normalizes skin cell turnover to keep pores clear, and it works on a weeks-not-days timeline. The value pack of two tubes covers a longer stretch of that routine without a second purchase.

  • 0.1% adapalene gel
  • Two 0.5 oz tubes
  • Unscented tube format
  • Anti-inflammatory acne treatment

Who it's for

Suited to people with mild to moderate acne who are ready to commit to a retinoid routine. Not a fit for anyone wanting a fast fix or who hasn't tried a retinoid before.

Strengths and trade-offs

Drawn from this product's published specifications.

What stands out
  • Two tubes cover months of nightly use
  • Unscented, plain formula for acne-prone skin
  • Dermatologist-grade retinoid at accessible pricing
What to check first
  • Retinoids commonly cause initial dryness or peeling
  • Results take weeks, not days
  • No fragrance-free claim listed despite being unscented

Performance notes

Adapalene works by speeding skin cell turnover so pores stay clearer, with anti-inflammatory benefits built into the formula. Most users see initial dryness or peeling before results show over several weeks of nightly use.

Specifications

BrandDifferin
Model302994920303-2a
Dimensions & fit
Item Weight2.6 ounces
Net Content Weight0.5 ounces
Capacity & performance
Age Range DescriptionAdult
Construction & materials
Material FeaturesNatural
Included components
Unit Count1 ounce
Package Quantity2
Package Type NameTube
Other details
Skin TypeAcne Prone
Number Of Items2
AsinB07N619Q2M
Customer Reviews{'ratings_count': '454', 'stars': '4.5'}
Recommended Uses For ProductAnti Inflammatory
Best Sellers Rank#182,179 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #382 in Facial Cleansing Gels
Model Number302994920303-2a
Item FormGel
Upc302990240603
ManufacturerGalderma
Scent NameUnscented
Manufacturer Part Number302994920303-2a

How it compares

This product against the closest alternatives we track in gels.

ProductAmazon ratingRatingsProductDome score
Differin Adapalene Gel 0.1% Acne TreatmentThis product4.5 / 54543.7 / 5
Simple Kind to Skin Refreshing Facial Wash GelBrand4.6 / 528,5004.6 / 5
patanjali Aloe Vera Gelpatanjali4.4 / 57,3004.5 / 5
Bioderma Sensibio Foaming Gel Gentle Face CleanserBioderma4.7 / 522,7004.3 / 5
Nature Republic Mild & Moisture Aloe Vera Watery GelNature Republic4.6 / 513,2004.1 / 5
Frequently asked

Questions about the Differin 302994920303-2a

Common buyer questions answered straight from the product spec data - no fluff, no "it depends".

What is the active ingredient in Differin Adapalene Gel?

Adapalene 0.1%, a retinoid that normalizes skin cell turnover to help treat acne.

How many tubes come in this pack?

Two 0.5 ounce tubes, combining for 1 ounce total.

Is this gel scented?

No, it's listed as unscented.