US
Differin

Differin Adapalene Gel 0.1% Acne Treatment 45 g

  • Skin Type: All
  • Special Ingredients: Adapalene
  • Product Benefits: Acne Preventing
  • Target Use Body Part: Face

Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

A standard 0.1% adapalene gel sized for months of regular use, useful for acne prevention over time rather than as a fast fix for an active breakout.

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ASIN: B01M114813Category: Skin Care Gels

Overview

Differin's adapalene gel is a 0.1% retinoid formulated for acne, sold in a 45 gram (1.6 ounce) size described as up to a 90 day supply. It is fragrance free and labeled for all skin types on the face.

Adapalene is a retinoid available over the counter at 0.1% strength, generally used to prevent new acne from forming rather than to treat existing breakouts overnight, and it is applied in thin layers on the whole face rather than spot treated. Retinoids commonly cause dryness or peeling when a routine starts, which is not addressed in the listing itself.

  • 0.1% adapalene gel
  • 45 gram, up to 90 day supply
  • Fragrance free
  • Formulated for the face

Who it's for

Fits buyers looking for an over the counter retinoid for ongoing acne prevention on the face. Not intended for spot treatment of a single blemish, and not a fit for anyone new to retinoids without knowing the typical adjustment period.

Pros and cons

Pros
  • 0.1% adapalene, an established acne preventing retinoid
  • Sized for up to a 90 day supply
Cons
  • Preventive, not a fast fix for active breakouts
  • Retinoids commonly require an adjustment period the listing does not cover

Performance notes

At 0.1% adapalene, this sits at the standard over the counter strength, applied as a thin layer across the face rather than spot treated on individual blemishes. The 45 gram size is described as up to a 90 day supply, which frames it for a several month routine rather than short term use.

Specifications

BrandDifferin
Dimensions & fit
Item Weight0.1 pounds
Size1.58 Ounce (Pack of 1)
Package Size Name90 Day Supply
Construction & materials
Material FeaturesFragrance Free
Included components
Unit Count0.1 pounds
Other details
Skin TypeAll
Special IngredientsAdapalene
Product BenefitsAcne Preventing
Target Use Body PartFace
Item FormGel
Scent NameUnscented
AsinB01M114813
Customer Reviews{'ratings_count': '4,012', 'stars': '4.6'}
Best Sellers Rank#80,794 In Beauty & Personal Care (See Top 100 In Beauty & Personal Care) #175 In Facial Cleansing Gels #2,835 In Facial Treatments & Masks
ManufacturerGalderma Laboratories, Inc
Manufacturer Part Number302994910458
Upc302994910458

Frequently asked questions

What is the adapalene concentration in Differin gel?

0.1 percent.

How long does the 45 gram Differin gel last?

It is listed as up to a 90 day supply.

Is Differin adapalene gel fragrance free?

Yes, it is labeled fragrance free.