Zymox Advanced Otic Plus Ear Solution Without Hydrocortisone 1.25 oz

Size: 0.08 Pounds
Item Weight: 0.01 Ounces
Color: Black
Fabric Type: 100%

Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

A straightforward once-daily ear treatment for infections, worth stocking if your vet has ruled out a punctured eardrum and you want to skip the steroid.

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ASIN: B072DVND3ZCategory: Pet Ear Care Products

Overview

Zymox Advanced Formula Otic Plus is an enzymatic ear solution for dogs and cats, formulated in this version without hydrocortisone. It targets ear infections with a once-daily topical routine rather than a course of prescription drops.

The line is built around an enzyme system rather than antibiotics, and this Plus version skips the steroid found in some Zymox variants. That makes it a option for owners who want to avoid hydrocortisone but still need daily infection management. The listing does not include clinical claims beyond usage instructions, so treat it as a topical aid rather than a diagnosis-and-cure product.

1.25 fl oz bottle
Hydrocortisone-free enzymatic formula
Once-daily application for 7 to 14 days
For both dogs and cats

Who it's for

Owners of dogs or cats with diagnosed ear infections who want a hydrocortisone-free option they can apply at home. Not intended for pets with a ruptured or punctured eardrum.

Pros and cons

Pros

No hydrocortisone in this formula version
Single daily application, no separate cleaning step required first
Labeled safe for extended use on chronic ear issues

Cons

Not usable if the eardrum is punctured
Applied to an un-cleaned ear, which some owners may find counterintuitive
Small 1.25 oz bottle for a multi-week course

Performance notes

The bottle is shaken and applied directly onto the un-cleaned ear, filling the canal, then massaged in and wiped of excess. Amazon's listing specifies once a day for 7 days for standard cases or 14 days for chronic issues, and states the formula is meant to be safe for extended use on persistent cases.

Specifications

Dimensions & fit
Brand	ZYMOX
Size	0.08 Pounds
Item Weight	0.01 Ounces
Item Dimensions L X W	10 × 10 inches
Capacity & performance
Age Range Description	Adult
Construction & materials
Color	Black
Fabric Type	100%
Included components
Unit Count	1.3 fl oz
Other details
Number Of Items	1
Asin	B072DVND3Z
Manufacturer	Lambert Vet Supply
Customer Reviews	{'ratings_count': '1,658', 'stars': '4.6'}
Model Name	ZYMOX PLUS ADVANCED FORMULA OTIC DOG AND CAT EAR INFECTION SOLUTION
Item Type Name	Item
Best Sellers Rank	#16,560 In Pet Supplies (See Top 100 In Pet Supplies) #15 In Cat Ear Care #150 In Dog Ear Care
Recommended Uses For Product	ear infections
Manufacturer Part Number	1201AF
Upc	667334421255
Model Number	1201AF
Additional Features	Hydrocortisone-Free
Blanket Form	Comforter
Theme	Animals
Product Care Instructions	Shake well before use. Apply liberally to un-cleaned ear, filling the ear canal. Gently massage and work into affected area. Wipe to remove excess. Apply once a day for 7 days or 14 days for chronic issues. This product is safe for extended use on persistent cases. Do not use on punctured ear drums. Keep out of reach of children.