US
Differin

Differin Adapalene Acne Treatment Gel 15 g Pump

  • Item Volume: 15 fl oz
  • Skin Type: All, Sensitive
  • Active Ingredients: Adapalene 0.1%
  • Special Ingredients: Retinoid

Last refreshed Aug 4, 2026 · Based on the Amazon listing and published specifications, not hands-on testing.

Our verdict

A 0.1% adapalene retinoid gel for acne-prone skin, sized for a 30-day course and requiring consistent use before results show.

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ASIN: B07ZTMXJVKCategory: Skin Care Gels

Overview

Differin Acne Treatment Gel is an over-the-counter retinoid formulated with 0.1% adapalene, sold as a 15g pump meant to last about 30 days of once-daily use. It targets acne and is made by Galderma Laboratories.

Adapalene is the same retinoid class ingredient long available by prescription before Differin's switch to over the counter, and it works over weeks rather than days, so the 30-day supply size matches its typical use pattern rather than being an arbitrary trial size. The oil-free, fragrance-free, non-comedogenic formulation is built for acne-prone skin that still needs to avoid clogging pores further.

  • 15g pump, roughly a 30 day supply
  • 0.1% adapalene retinoid gel
  • Oil free, fragrance free, non-comedogenic
  • Made by Galderma Laboratories

Who it's for

Fits people managing ongoing acne who want a retinoid gel rather than a spot treatment, applied to the whole face nightly. Not for anyone expecting fast results, since retinoids typically take several weeks to show a visible change.

Pros and cons

Pros
  • 0.1% adapalene retinoid, the over-the-counter strength active
  • Oil free and non-comedogenic
Cons
  • Takes weeks of consistent use to show results
  • Retinoid adjustment period can bring dryness or peeling

Performance notes

Adapalene works by normalizing the shedding of skin cells inside the pore lining, which reduces new clogged pores forming over time rather than treating existing breakouts directly. That mechanism is why retinoid gels like this one are applied preventively across the whole face rather than dabbed onto individual spots, and why initial dryness or peeling during the first weeks is common as skin adjusts.

Specifications

BrandDifferin
Dimensions & fit
Item Weight0.11 pounds
Size15g (30 Day Supply)
Capacity & performance
Item Volume15 fl oz
Construction & materials
Material FeaturesOil Free, Alcohol Free, Fragrance Free, Non Comedogenic
Other details
Skin TypeAll, Sensitive
Active IngredientsAdapalene 0.1%
Special IngredientsRetinoid
Product BenefitsAnti-Acne
Target Use Body PartFace
Item FormGel
Scent NameUnscented
Container TypeBottle
AsinB07ZTMXJVK
Customer Reviews{'ratings_count': '8,355', 'stars': '4.4'}
ManufacturerGalderma Laboratories, Inc
Manufacturer Part NumberB07ZTMXJVK
Model Number0299.491010
Upc302994910106
Item Type NameRetinoid
Set NameDifferin Gel Acne Treatment

Frequently asked questions

How long does one Differin 15g pump last?

It is sized as roughly a 30-day supply with once-daily use.

Is Differin Gel oil free?

Yes, the formula is oil free and non-comedogenic.

What is the active ingredient in Differin Gel?

Adapalene at 0.1%, a retinoid.